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Sponsor(s): Sponsoring Section/Society: ASA-BIOMETRICS

Session Time: 2:00- 3:50 Monday

Estimated Audience Size: 250-300

A/V Request: Overhead Projector, 2*2 slide projector

Session Title: Estimating the Cumulative Risk (Penetrance) Associated with a Mutation

Theme Session: No $\quad$ Applied Session: Yes

Organizer: Gail, Mitchell  

Session Timing: 110 minutes total...please allocate Opening Remarks by Chair - 5 or 0 minutes First Speaker - 30 minutes (or 25) Second Speaker - 30 minutes Third Speaker - 30 minutes Discussant - 10 minutes (or none) Floor Discussion - 10 minutes (or 5 or 15)

Chair: Olson, Jane M.  

1. Penetrance - What Is It? $\quad$ Wijsman, Ellen  

2. A Comparision of Cohort, Case-Control and Family Study Designs for Estimating Penetrance $\quad$ Gail, Mitchell  

3. Estimating Disease Risk From Family-Based Case-Control Studies and Improving Penetrance Estimates With Hierarchical Modeling $\quad$ Witte, John  

Discussant: Schaid, Daniel J.  

List of speakers who are nonmembers: None

David Scott