John Fricks
Penn State University

Multiple Scales in Molecular Motor Models

Molecular motors, such as kinesin and dynein, carry cargos through a cell along a microtubule network. The heads of these motors step along a microtubule and are on the order of nanometers, while the cargo can be on the order of hundreds of nanometers. In addition, multiple motors may be connected to a single cargo. In this talk, we will discuss the application of semi-Markov models to link the actions of the heads to the stepping of the motor. In addition, we analyze multiple motors combined with the cargo across relevant temporal and spatial scales by performing a dimensional analysis and applying relevant averaging theorems.