Books

 

Monograph

Kimmel M and Axelrod DE. Branching Processes in Biology. Springer, New York. To appear, March 2002.

 

Edited Volumes

Arino, O., Kimmel, M. and Witten, M. Proceedings of the Conference on Mathematical Population Dynamics, November 20-22, 1986. Published as vol. 18, no. 10/11, Computers and Mathematics with Applications, Pergamon Press, New York, 1989, pp. 851-982.

Arino, O., Axelrod, D.E. and Kimmel, M. Mathematical Population Dynamics: Proceedings of the Second International Conference. Marcel Dekker, New York, 1991, pp. 1-780.

M. Kimmel and A. Swierniak, Control and Modeling of Cancer Cell Populations. Special Issue of Applied Mathematics and Computer Science, Vol.4, No. 2, 1994.

Arino, O., Axelrod, D.E. and Kimmel, M. Mathematical Population Dynamics: Proceedings of the Third International Conference. Wuerz Publishing Co., Winnipeg, Manitoba, 1995, vol. 1, pp. 1-393; vol. 2, pp. 1-370.

Arino, O., Axelrod, D.E. and Kimmel, M. Mathematical Population Dynamics: Proceedings of the Fourth International Conference. World Scientific, Singapore, 1998, pp. 1-920.

 

Published Papers

1.                  Kimmel, M. and M. Wazewska-Czyzewska. Analysis of Different Variants of Erythrocyte Survival with the Use of Digital Computer. Acta Haemat Pol 10: 1-6, 1979. 

2.                  Kimmel, M. Mathematical Model of the Proliferation Cycle of Lymphoblastic Leukemia Cells. Acta Haemat Pol 10: 91-98, 1979. 

3.                  Kimmel, M. An Approach to Cellular Population Kinetics Investigation and Modeling. Proc IV Int Symp System, Modeling, Control. Lodz University Press, Lodz (Poland), 2: 100-105, 1979. 

3a.              Kimmel M (1978) Analysis and modeling of the nonsteady assembly line process (in Polish, English abstract). Technical Reports of the Silesian Technical University, series Automation (Zeszyty Naukowe Politechniki Slaskiej, seria Automatyka), 43: 45-52. 

3b.              Kimmel M (1979) Statistical problems in the assembly process (in Polish, English abstract). Technical Reports of the Silesian Technical University, series Automation (Zeszyty Naukowe Politechniki Slaskiej, seria Automatyka), 47: 107-116. 

3c.              Kimmel M (1980) Application of a Monte-Carlo method to the sequence optimization in the sequencing problem (in Polish, English abstract). Technical Reports of the Silesian Technical University, series Automation (Zeszyty Naukowe Politechniki Slaskiej, seria Automatyka), 53: 101-110. 

3d.              Kimmel M (1980) Application of the point process theory to the assembly knot design (in Polish, English abstract). Technical Reports of the Silesian Technical University, series Automation (Zeszyty Naukowe Politechniki Slaskiej, seria Automatyka), 54: 89-97. 

3e.              Kimmel M (1982) Specific problems in the queuing theory related to the discrete industrial processes. I: Basic models (in Polish, English abstract). Technical Reports of the Silesian Technical University, series Automation (Zeszyty Naukowe Politechniki Slaskiej, seria Automatyka), 65: 89-99. 

3f.               Kimmel M (1982) Specific problems in the queuing theory related to the discrete industrial processes. II: Limit laws for a simple process (in Polish, English abstract). Technical Reports of the Silesian Technical University, series Automation (Zeszyty Naukowe Politechniki Slaskiej, seria Automatyka), 65: 101-109. 

3g.              Kimmel M (1982) Specific problems in the queuing theory related to the discrete industrial processes. III: Further limit properties (in Polish, English abstract). Technical Reports of the Silesian Technical University, series Automation (Zeszyty Naukowe Politechniki Slaskiej, seria Automatyka), 65: 111-120. 

4.                  Kimmel, M. Cellular Population Dynamics I: Model Construction and Reformulation. Math Biosci 48: 211-224, 1980. [10]

5.                  Kimmel, M. Cellular Population Dynamics II: Investigation of Solutions. Math Biosci 48: 225-239, 1980. [8]

6.                  Kimmel, M. A Modified Periodogram Method as a Tool for Investigation of Randomly Disturbed Biorythms. Bull Acad Sci Pol Biol Ser 27: 1047-1052, 1979. 

7.                  Kimmel, M. Time-Discrete Model of Cellular Population Dynamics. Systems Sci 6: 343-360, 1980. 

8.                  Kimmel, M. Stability of Control Coupling of Red Blood Cell System (in Polish, English abstract). Post Cyber 4: 25-38, 1981. 

9.                  Kimmel, M. Integro-Differential Equations in Cellular Population Dynamics. Functional Differential Systems and Related Topics (Kisielewicz, M., ed.). Math Inst Pol Acad Sci, Zielona Gora (Poland), pp. 149-160, 1980. 

10.             Kimmel, M. General Theory of Cell Cycle Dynamics Based on Branching Processes in Varying Environment (Rotenberg M, ed). Biomathematics and Cell Kinetics Elsevier/North Holland Biomedical Press, Amsterdam, pp. 357-375, 1981. [5]

11.             Kimmel, M. An Equivalence Result for Integral Equations with Application to Branching Processes. Bull Math Biol 44: 1-15, 1982. [2]

12.             Kimmel, M. Branching Processes in Varying Environment as Dynamical Systems with Heredity. Functional Differential Systems and Related Topics II (Kisielewicz, M., ed.). Math Inst Pol Acad Sci, Zielona Gora (Poland), pp. 164-177, 1981. 

13.             Kimmel, M. The Point Process Approach to Age- and Time-Dependent Branching Processes. Adv Appl Prob 15: 1-20, 1983. 

14.             Kimmel, M., B. Kimmel and J. Skierski. Mathematical Model of Leukemic Cells Circulation in the Mouse. Math Biosci 67: 81-99, 1983. [1]

15.             Kimmel, M., F. Traganos and Z. Darzynkiewicz. Do all Daughter Cells Enter the `Indeterminate' (`A') State of the Cell Cycle? Analysis of Stathmokinetic Experiment on L1210 Cells. Cytometry 4: 191-201, 1983. [19]

16.             Kimmel, M. and M. Wazewska-Czyzewska. Stochastic Approach to the Process of Red Cell Destruction. Appl Mathematicae 17: 217-225, 1982. 

17.             Kimmel, M. and A. Swierniak. On a Certain Optimal Control Problem Related to the Optimal Chemotherapy of Leukemia. (in Polish, English abstract). Technical reports of the Silesian Technical University, Series Automation (Zeszyty Naukowe Politechniki Slaskiej, Seria Automatyka) 65: 121-130, 1982. 

17a.          Wojtusiak J; Kisiel E; Kimmel M The duration of larval development and individual larval instars in singly reared caterpillars of Saturnia pavonia L. (Lepidoptera, Saturniidae).Folia Biol (Krakow) 30: 21-7, 1982 

18.             Kimmel, M., Z. Darzynkiewicz, O. Arino and F. Traganos. Analysis of a Cell Cycle Model Based on Unequal Division of Metabolic Constituents to Daughter Cells During Cytokinesis. J Theor Biol 110: 637-664, 1984. [29]

19.             Darzynkiewicz, Z., S. Carter and M. Kimmel. Effects of Tritium Labeled Uridine on the Cell Cycle Progression of L1210 Cells. Cell Tissue Kinet 17: 641-655, 1984. [4]

20.             Flehinger, B.J., M.R. Melamed, M.B. Zaman, R.J. Heelan, M. Kimmel, W.B. Perchick and M. Martini. (1984) Screening for Early Detection of Lung Cancer in New York. A report of a UICC international workshop, Venice, Italy November 14-16, 1983 (Prorok PC, Miller AB, eds). UICC International Reports Series, Vol. 78, Geneva, pp. 123-135. 

21.             Flehinger, B.J. and M. Kimmel. The Natural History of Lung Cancer in a Periodically Screened Population. IBM Res Rep, RC 11027, 1-44, 1985. 

22.             Kimmel, M. and F. Traganos. Kinetic Analysis of a Drug Induced G2 Block in Vitro. Cell Tissue Kinet 18: 91-110, 1985. [2]

23.             Arino, O. and M. Kimmel. Asymptotic Analysis of a Functional-Integral Equation Related to Cell Population Kinetics. Trends in the Theory and Practice of Non-Linear Analysis. (Lakshmikantham, V., ed.). North Holland, Amsterdam, pp. 27-32, 1985. 

23a.          Kimmel M; Bajkowska K; Rytwinski K A simple model of cell cycle dynamics with application to estimation of cell cycle parameters. Acta Haematologica Polonica 16: 1-6, 1985. 

24.             Kimmel, M. Bayesian Birds: Concerning the Paper of RF Green. (In Polish, English abstract). Ann Pol Math Soc Ser II Appl Math 22: 175-178, 1983. 

25.             Kimmel, M. Nonparametric Analysis of Stathmokinesis. Math Biosci 74: 111-123, 1985. [4]

26.             Kimmel, M. and O. Arino. Complex Proliferative Systems: Formal Description and Qualitative Analysis. Systems Sci 9: 135-161, 1983. 

27.             Kimmel, M., Z. Darzynkiewicz and L. Staiano-Coico. Stathmokinetic Analysis of Human Epidermal Cells in Vitro. Cell Tissue Kinet 19: 289-304, 1986. [18]

28.             Staiano-Coico, L., P.J. Higgins, Z. Darzynkiewicz, M. Kimmel, A. Gottlieb, I. Pagan-Charry, M.R. Madden, J.L. Finkelstein and J.M. Hefton. Human Keratinocyte Culture: Identification and Staging of Epidermal Cell Subpopulations. Journal of Clinical Invest 77: 396-404, 1986.

29.             Kimmel, M. Does Competition for Food Imply Skewness? Math Biosci 80: 239-264, 1986. [5]

30.             Kimmel, M. and F. Traganos. Estimation and Prediction of Cell Cycle Specific Effects of Anticancer Drugs. Math Biosci 80: 187-208, 1986. [7]

31.             Darzynkiewicz, Z., F. Traganos and M. Kimmel. Assay of Cell Cycle Kinetics by Multivariate Flow Cytometry Using the Principle of Stathmokinesis. Techniques in Cell Cycle Analysis (Gray, J.E. and Z. Darzynkiewicz, eds.). Humana Press, Clifton, NJ, pp. 291-336, 1986. 

32.             Arino, O. and M. Kimmel. Stability Analysis of Models of Cell Production Systems. Math Modeling 7: 1269-1300, 1986. [1]

33.             Arino, O. and M. Kimmel. Asymptotic Analysis of a Cell Cycle Model Based on Unequal Division. SIAM J Appl Math 47: 128-145, 1987. [15]

34.             Brustein, S., D.A. Filippa, M. Kimmel, P.H. Lieberman and P.P.Rosen. Malignant Lymphoma of the Breast: A Study of 53 Patients. Ann Surgery 205: 144-150, 1987. [39]

35.             Flehinger, B.J. and M. Kimmel. The Natural History of Lung Cancer in a Periodically Screened Population. Biometrics 43: 127-144, 1987. [20]

36.             Badalament, R.A., M. Kimmel, H. Gay, E.S. Cibas, W.F. Whitmore, H.W. Herr, W.R. Fair and M.R. Melamed. The Sensitivity of Flow Cytometry Compared with Conventional Cytology in the Detection of Superficial Bladder Carcinoma. Cancer 59: 2078-2085, 1987. 

37.             Kimmel, M. Metabolic Events in the Cell Cycle of Malignant and Normal Cells. A Mathematical Modeling Approach. Cancer Modeling (Thompson, J.R. and B. Brown, eds.). Marcel Dekker, New York, pp. 215-235, 1987. 

38.             Badalament, R., D.K. Hermansen, M. Kimmel, H. Gay, H.W. Herr, W.R. Fair, W.F. Whitmore Jr. and M.R. Melamed. The Sensitivity of Bladder Wash Flow Cytometry, Bladder Wash Cytology and Voided Cytology in the Detection of Bladder Carcinoma. Cancer 60: 1423-1427, 1987. 

39.             Kinne, D.W., J.A. Butler, M. Kimmel, B.J. Flehinger, C. Menendez-Botet and M. Schwartz. Estrogen Receptor Protein of Breast Cancer in Patients with Positive Nodes: High Recurrence Rates in the Postmenopausal Estrogen Receptor-Negative Group. Arch Surg 122: 1303-1306, 1987. 

40.             Traganos, F., M. Kimmel, C. Bueti and Z. Darzynkiewicz. Effects of Inhibition of RNA or Protein Synthesis on CHO Cell Cycle Progression. J Cell Physiol 133: 277-287, 1987. 

41.             Staiano-Coico, L., D.P. Hajjar, J.M. Hefton, K. Hajjar and M. Kimmel. Interaction of Arterial Cells: III. Stathmokinetic Analyses of Smooth Muscle Cells Cocultured with Endothelial Cells. J Cell Physiol 134: 485-490, 1988. 

42.             Kimmel, M. and O. Arino. On Active Linear Compartments. Math Comp Modeling 11: 1189-1194, 1988. 

43.             Flehinger, B.J., M. Kimmel and M.R. Melamed. The Natural History of Adenocarcinoma - Large Cell Carcinoma of the Lung: Conclusions from Screening Programs in New York and Baltimore. J Natl Cancer Inst 80: 337-344, 1988. [16]

44.             DeAngelis, P., M. Kimmel, M. Lacher, D. Filippa and M.R. Melamed. T-Cell Subsets in Peripheral Blood of Patients with Newly-Diagnosed and Post-treatment Hodgkin's and Non-Hodgkin's Lymphomas: Analysis by Monoclonal Antibody Staining and Flow Cytometry. Acta Cytol 10: 235-242, 1988. 

45.             Lieberman, P.H., M.F. Brennan, M. Kimmel, R.A. Erlandson, P. Garin-Chesa and B.J. Flehinger. Alveolar Soft-Part Sarcoma. A Clinico-Pathologic Study of Half a Century. Cancer 63: 1-13, 1989. 

46.             Rosen, P.P., M. Kimmel and D. Ernsberger. Mammary Angiosarcoma: The Prognostic Significance of Tumor Differentiation. Cancer 62: 2145-2151, 1988. 

47.             Cibas, E.S., M.R. Melamed, M.B. Zaman and Kimmel, M. The Effects of Tumor Size and Tumor Cell DNA Content on Survival of Patients with Stage I Adenocarcinoma of the Lung. Cancer 63: 1552-1556, 1989. 

48.             Kimmel, M. and O. Arino. A System of Differential Equations Modeling the G1 Phase of the Cell Cycle. Comp Math Appl 18: 907-917, 1989. 

49.             Arino, O. and M. Kimmel. Asymptotic Behavior of a Nonlinear Functional-Integral Equation of Cell Kinetics with Unequal Division. J Math Biol 27: 341-354, 1989. 

50.             Kunicka, J.E., W. Olszewski, P.P. Rosen, M. Kimmel, M.R. Melamed and Z. Darzynkiewicz. DNA in Situ Sensitivity to Denaturation as a Marker of Human Breast Tumors. Cancer Res. 49: 6347-6351, 1989. 

51.             Rosen, P.P. and M. Kimmel. Juvenile Papillomatosis of the Breast: A Follow-up Study of 41 Patients Having Biopsies Before 1979. Amer J Clin Path 93: 599-603, 1990. 

52.             Bretton, P.R., H.W. Herr, W.F. Whitmore, R.A. Badalament, M. Kimmel, J. Provet, W.R. Fair and M.R. Melamed. Intravesical Baccillus Calmette-Guerin Therapy for in Situ Transitional Cell Carcinoma Involving the Prostatic Urethra. J Urology 141: 853-855, 1989. 

53.             Kimmel, M., A. Grossi, J. Amuasi and A.M. Vannucchi. Non-parametric Analysis of Platelet Lifespan. Cell Tissue Kinet 23: 191-202, 1990. 

54.             Hermansen, D.K., R.A. Badalament, P.R. Bretton, M. Kimmel, C.M. Aswad, W.F. Whitmore Jr. and M.R. Melamed. Voided Urine Flow Cytometry in Screening High-Risk Patients for the Presence of Bladder Cancer. J Occup Med 32: 894-897, 1990. 

55.             Traganos, F. and M. Kimmel. The Stathmokinetic Experiment: A Single-Parameter and Multiparameter Flow Cytometric Analysis. Methods in Cell Biology (Darzynkiewicz, Z. and H.A. Crissman, eds.). Academic Press, NY, 23: 249-270, 1990. 

56.             Rosen, P.P. and M. Kimmel. Occult Breast Carcinoma Presenting with Axillary Lymph Node Metastases: A Follow-up Study of 48 Patients. Hum Pathol 21: 518-523, 1990. 

57.             Kimmel, M. and D.E. Axelrod. Mathematical Models of Gene Amplification with Applications to Cellular Drug Resistance and Tumorigenicity. Genetics 125: 633-644, 1990. [9]

58.             Greenlee, P.G., D.A. Filippa, F.W. Quimby, A.K. Patnaik, S.E. Calvano, R.E. Matus, M. Kimmel, A.I. Hurvitz and P.H. Lieberman. Lymphomas in Dogs: A Morphologic, Immunologic, and Clinical Study. Cancer 66: 480-490, 1990. [44]

59.             Myc, A., P. DeAngelis, M. Kimmel, M.R. Melamed and Z. Darzynkiewicz. Retention of the Mitochondrial Probe Rhodamine 123 in Normal Lymphocytes and Leukemic Cells in Relation to the Cell Cycle. Exp Cell Res 192: 198-202, 1991. [0]

60.             Bretton, P.R., Z. Darzynkiewicz, E. Henry, M. Kimmel, W.R. Fair and M.R. Melamed. DNA in Situ Sensitivity to Denaturation in Bladder Cancer and its Correlation with Tumor Stage. Cancer Res 50: 7912-7914, 1990. 

61.             Abati, A., M. Kimmel and P.P. Rosen. Apocrine Mammary Carcinoma: A Clinicopathologic Study of 72 Cases. Amer J Clin Path 94: 371-377, 1990. 

62.             Arino, O., M. Kimmel and M. Zerner. Analysis of a Cell Population Model with Unequal Division and Random Transition. Mathematical Population Dynamics (Arino, O., D.E. Axelrod and M. Kimmel, eds.). Marcel Dekker, NY. pp.3-12, 1991. [1]

63.             Arino, O. and M. Kimmel. Asymptotic Behavior of Nonlinear Semigroup Describing a Model of Selective Cell Growth Regulation. Journal of Mathematical Biology 29: 289-314, 1991. [3]

64.             Flehinger, B.J. and M. Kimmel. Screening for Cancer in Relation to the Natural History of Disease. Mathematical Population Dynamics (Arino, O., D.E. Axelrod and M. Kimmel, eds.). Marcel Dekker, NY, pp. 383-390, 1991. [0]

65.             Darzynkiewicz, Z., F. Traganos, M. Kimmel and A. Myc. Kinetic and Metabolic Heterogeneity of Cells in the Cell Cycle. Stochastic Modeling in Biology. Relevant Mathematical Concepts and Recent Applications (Tautu, P., ed.). World Scientific Publishing, 1990. 

66.             Enker, W.E., M. Kimmel, E.S. Cibas, M.L. Cranor and M.R. Melamed. DNA/RNA Content and Proliferative Fractions of Colorectal Carcinomas: A Five-Year Prospective Study Relating Flow Cytometry to Survival. J Natl Cancer Inst 83: 701-707, 1991. [32]

67.             Kimmel, M. and O. Arino. Cell Cycle Kinetics with Supramitotic Control, Two Cell Types and Unequal Division: A Model of Transformed Embryonic Cells. Math Biosci 105: 47-79, 1991. [8] 

68.             Kimmel, M. and B.J. Flehinger. Non-Parametric Estimation of the Size-Metastasis Relationship in Solid Cancers. Biometrics, 47: 987-1004, 1991. [7]

69.             Bretton, P.R., H.W. Herr, M. Kimmel, W.R. Fair, W.F. Whitmore, Jr. and M.R. Melamed. Flow Cytometry as a Predictor of Response and Progression in Patients with Superficial Bladder Cancer Treated with Bacillus Calmette-Guerin. The Journal of Urology 141: 1332-1336, 1989. 

70.             Bretton PR; Herr HW; Kimmel M; Whitmore WF Jr; Laudone V; Oettgen HF; Fair WR The response of patients with superficial bladder cancer to a second course of intravesical bacillus Calmette-Guerin. The Journal of Urology 143: 710-2, 1990. 

71.             Sanchez, E., O. Arino and M. Kimmel. Noncompact Semigroups of Operators Generated by Cell Kinetics Models. Diff Integr Equat 4: 1233-1249, 1991. [1]

72.             Kimmel, M. and D.E. Axelrod. Unequal Cell Division, Growth Regulation and Colony Size of Mammalian Cells: A Mathematical Model and Analysis of Experimental Data. Journal of Theoretical Biology 153: 157-180, 1991. [11]

73.             Flehinger, B.J., M. Kimmel and M.R. Melamed. The Effect of Surgical Treatment on Survival from Early Lung Cancer: Implications for Screening. Chest 101: 1013-1018, 1992. [34]

74.             Kimmel, M., D.E. Axelrod and G.M. Wahl. A Branching Process Model of Gene Amplification Following Chromosome Breakage. Mutation Res. 276: 225-239, 1992. [16]

75.             Swierniak A., and M. Kimmel. Optimal Control Application to Leukemia Chemotherapy Protocols Design, (in Polish, English abstract). Technical reports of the Silesian Technical University, Series Automation (Zeszyty Naukowe Politechniki Slaskiej, Seria Automatyka) 73: 261-277, 1984. 

76.             Swierniak A., and M. Kimmel. Cancer Cell Synchronization and Recruitment as Optimal Control Problems, Proc. of 13th Worls IMACS Congress, Dublin vol. 3: 1461-1462, 1991. 

77.             Kapuscinski, Jan, and Kimmel, Marek, Thermodynamical Model of Mixed Aggregation of Intercalators with Caffeine in Aqueous Solution. Biophysical Chemistry 46: 153-163, 1993. [4]

78.             Flehinger, B.J., M. Kimmel, T. Polyak, and M.R. Melamed. 1993 Screening for Lung Cancer: The Mayo Lung Program Revisited. Cancer 72: 1573-1580. [11]

79.             Arino, O. and M. Kimmel. Comparison of Approaches to Modeling of Cell Population Dynamics. SIAM Journal of Applied Mathematics 53: 1480-1504, 1993. [2]

80.             Kusuda L; Kimmel M; Fair WR; Melamed M Hypocellular bladder wash specimens and their clinical significance. The Journal of Urology 150: 1123-5, 1993. [1]

81.             Kimmel, M. and D. Stivers. A Time-Continuous Branching Process Model of Unstable Gene Amplification. Bulletin of Mathematical Biology, 56: 337-357, 1994. [2]

82.             Kimmel, M. and D. Axelrod. Fluctuation Test for Two-Stage Mutations: Application to Gene Amplification. Mutation Research, 306: 45-60, 1994. [1]

83.             Axelrod D.E., K.A. Baggerly and M. Kimmel. Gene Amplification by Unequal Sister Chromatid Exchange: Probabilistic Modeling and Analysis of Drug Resistance Data. Journal of Theoretical Biology, 168: 151-159, 1994. [2]

84.             Kimmel, M. and O. Arino. Two Simple Models of Almost the Same Population with Very Different Dynamics. Mathematical Biosciences, 122: 183-200, 1994. [0]

85.             M. Kimmel. Rapid Genome Evolution and Cancer: A Modeling Perspective. Applied Mathematics and Computer Science, Special Issue (M. Kimmel, A. Swierniak, eds.) 4: 163-177, 1994. 

86.             O. Arino and M. Kimmel. A Non-Differentiable Semigroup Generated by a Model of Cell Population Dynamics. Applied Mathematics and Computer Science, Special Issue (M. Kimmel, A Swierniak, eds.) 4: 211-222, 1994. 

87.             Flehinger, B.J., and M. Kimmel. Early Lung Cancer Detection: Clinical Trials and Statistical Models. Case Studies in Biometry. (Lange, N., and L. Ryan, eds.). Wiley, NY. 1994, pp. 301-322. [2]

88.             Gelder-Ehm, M.E., M. Kimmel and R. W. Cottingham. Methods of Error Detection in Genetic Linkage Data for Human Pedigrees. Journal of Biological Systems. 3: 13-25, 1995. [0]

89.             Baggerly, K.A. and M. Kimmel. Emergence of Stable DNA Repeats from Random Sequences under Unequal Sister Chromatid Exchange. Proceedings of the I World Congress of Nonlinear Analysts, Tampa, Florida, August 1992. Walter de Gruyter, Berlin, 1995, 3409-3418. 

90.             Stivers, D.N. and M. Kimmel. On the clonal inheritance model of cell proliferation. Proceedings of the I World Congress of Nonlinear Analysts, Tampa, Florida, August 1992. Walter de Gruyter, Berlin, 1995, pp. 3401-3408. 

91.             Arino O., Kimmel M. and Webb G.F. Mathematical modeling of the loss of telomere sequences. Journal of Theoretical Biology . 177: 45-57, 1995. [5]

92.             Gelder Ehm M., Kimmel M. and Cottingham R.W. Error Detection for Genetic Data, Using Likelihood Methods. American Journal of Human Genetics. 58: 225-234, 1996. [0]

93.             Kimmel M., Chakraborty R., Stivers D.N. and Deka R. Dynamics of repeat Polymorphisms under Forward-Backward Mutation Models: Within- and Between-Population Variability at Microsatellite Loci. Genetics, 1996 [15] 

94.             Stivers D.N. and Kimmel M. A Continuous-Time, Multi-Type Generational Inheritance Branching Process Model of Cell Proliferation with Clonal Memory. Nonlinear World, 3: 385-399, 1996.  

95.              Stivers D.N., Kimmel M. and Axelrod D.E. A Discrete-Time, Multi-Type Generational Inheritance Branching Process Model of Cell Proliferation. Mathematical Biosciences, 137: 25-50, 1996. [1]

96.              Swierniak A., Polanski A. and M. Kimmel. Optimal Control Problems Arising in Cell-Cycle-Specific Chemotherapy. Cell Proliferation, 1996. [0]

97.              Kimmel, M., O, Arino, and D.E. Axelrod. 1996. Backward/forward duality of branching processes and cell population dynamics. Pp. 233-240. In Differential Equations and Applications to Biology and to Industry. M. Martelli, K. Cooke, E. Cumberbatch, B. Tang and H. Thieme (eds.) World Scientific Publ. Co. Singapore. 

98.             M. Kimmel. Quasistationarity in a Branching Model of Division-within-Division. Classical and Modern Branching Processes (P. Jagers and K. Athreya, eds.) The IMA Volumes in Mathematics and Its Applications. Vol. 84. Springer, 1996, pp. 157-164. 

99.              Gawel B. and M. Kimmel. Iterated Galton-Watson Process. Journal of Applied Probability, 33: 949-959, 1996. [3]

100.         M. Kimmel and R. Chakraborty. Measures of Variation at Microsatellite Loci Under a General Stepwise Mutation Model. Theoretical Population Biology, 50: 345-367, 1996. [9]

101.          A. Swierniak, A. Polanski and M. Kimmel. Control problems arising in chemotherapy under evolving drug resistance. Preprints of the 13th World Congress of IFAC, Volume B, 411-416, 1996 

102.         R. Chakraborty, M. Kimmel, D.N. Stivers, R. Deka and L J. Davison. Relative Mutation Rates at Di-, Tri-, and Tetra-Nucleotide Microsatellite Loci Proc. Natl. Acad. Sci. USA,  94: 1041-1046, 1997 [23]

103.         Staudte R., Huggins R.M., Zhang J., Axelrod D.E., and M. Kimmel Estimating clonal heterogeneity and interexperiment variability with the bifurcating autoregressive model for cell lineage data. Mathematical Biosciences, 1997 [0] 

104.         Buhler J., Owerbach D., Schaffer A.A., Kimmel M. and Gabbay K.H.  Linkage analyses in type I diabetes mellitus using CASPAR, a software and statistical program for conditional analysis of polygenic diseases. Human Heredity, 1997, 47: 211-222. [4]

105.         Bat O., Kimmel M. and Axelrod D.E. Computer Simulation Of Expansions of DNA Triplet Repeats in the Fragile X Syndrome and Huntington's Disease. Journal of Theoretical Biology, 1997, 188: 53-67. [2]

106.         Engel H., Goodacre A., Keyhani A., Jiang S., Van N.T., Kimmel M., Sanchez-Williams G. and Andreeff M. Minimal residual disease in acute myelogenous leukemia and myelodysplastic syndromes: A follow-up study of patients in clinical remission. British Journal of Haematology, 1997, 99: 64-75. [3]

107.         Kimmel M., Swierniak A., Polanski A. Infinite-Dimensional Model of Evolution of Drug Resistance of Cancer Cells. Journal of Mathematical Systems, Estimation and Control, 1998 

108.         A. Polanski, M. Kimmel, R. Deka and R. Chakraborty. Population Dynamics Model of CTG Repeat Allele at DMPK Locus.  Math. Biosci., 1998, 147: 93-112. [0]

109.         Swierniak A., Polanski A. and M. Kimmel. Qualitative Analysis of the Infinite Model of Drug Resistance Evolution. In Advances in Mathematical Population Dynamics: Molecules, Cells and Man (Arino O., Axelrod D.E., and Kimmel M., eds.). World Scientific, Singapore, 1997, pp. 595-612.

110.         Bat O., Kimmel M. and Axelrod D.E.Computer Simulation Of Expansions Of CGG DNA Triplet Repeats in The Fragile X Syndrome. In Advances in Mathematical Population Dynamics: Molecules, Cells and Man (Arino O., Axelrod D.E., and Kimmel M., eds.). World Scientific, Singapore, 1997, pp. 47-67.

111.         A. Polanski, M. Kimmel and R. Chakraborty (1998) Application of a time-dependent coalescence process for inferring the history of population size changes from DNA sequence data. Proceedings of the National Academy of Sciences USA, 95: 5456-5461. [1]

112.         M. Kimmel, R. Chakraborty, J.P. King, M. Bamshad, W.S. Watkins and L.B. Jorde. (1998) Signatures of Population Expansion in Microsatellite Repeat Data. Genetics, 148: 1921-1930. [7]

113.         P. Olofsson, M. Kimmel (1999) Stochastic models of telomere shortening. Math Biosci. 158: 75-92. [0]

114.         Engel H, Drach J, Keyhani A, Jiang S, Van NT, Kimmel M, Sanchez-Williams G, Goodacre A, Andreeff M (1999) Quantitation of minimal residual disease in acute myelogenous leukemia and myelodysplastic syndromes in complete remission by molecular cytogenetics of progenitor cells. Leukemia. 13: 568-77. [0]

115.         Deka R, Guangyun S, Smelser D, Zhong Y, Kimmel M, Chakraborty R (1999) Rate and directionality of mutations and effects of allele size constraints at anonymous, gene-associated, and disease-causing trinucleotide loci. Mol Biol Evol. 16: 1166-1177. [0]

116.         A. Bobrowski and M. Kimmel (1999) Asymptotic behaviour of an operator exponential related to branching random walk models of DNA repeats. Journal of Biological Systems 7: 33-43. [0]

117.         Kimmel M (1999) Population Dynamics coded in DNA: Genetic traces of the expansion of modern humans. Physica A 273: 158-168.

118.         A. Bobrowski and M. Kimmel (1999) Dynamics of life history of a DNA repeat sequences, Archives of Control Sciences 9.:57-68.

119.         J. Polanska and M. Kimmel (1999) A model of dynamics of mutation, genetic drift and recombination in DNA –repeat genetic loci. Archives of Control Sciences 9.: 143-158.

120.         King JP, Kimmel M and Chakraborty R (2000) A power analysis of microsatellite-based statistics for inferring past population growth Mol. Biol. Evol. 17: 1859-1868.

121.         A. Bobrowski, M. Kimmel, O. Arino, R. Chakraborty (2001) A semigroup representation and asymptotic behavior of certain statistics of the Fisher-Wright-Moran coalescent. In Stochastic Processes: Theory and Applications (Handbook of Statistics series) C.R. Rao and D.N. Shanbhag, eds. Elsevier Science, Amsterdam.

122.         Renwick A, Davison L, Spratt H, King JP, Kimmel M (2001) DNA dinucleotide evolution in humans: fitting theory to facts. Genetics 159: 737-747.

123.         Olofsson O, Schwalb O, Chakraborty R, Kimmel M (2001) An application of a general branching process in the study of the genetics of aging. Journal of Theoretical Biology 213: 547-557.

124.         Gorlova OY, Kimmel M, Henschke C (2001) Modeling of long-term screening for lung carcinoma. Cancer 92: 1531-1540.

125.         Bobrowski A, Wang N, Chakraborty R, Kimmel M (2002) Non-homogeneous infinite sites model under demographic change: mathematical description and asymptotic behavior of pairwise distributions. Math Biosci. 175: 83-115.

126.         Trikka D, Fang Z, Renwick A, Jones SH, Chakraborty R, Kimmel M, Nelson D. (2002) Complex SNP-Based Haplotypes in Three Human Helicases:  Implications for Cancer Association Studies.  Genome Research 12:  627-639.

 

 

Papers Accepted

 K. Fujarewicz, M. Kimmel, J. Rzeszowska-Wolny and A. Swierniak. A note on classification of gene expression data using support vector machines. Submitted to Journal of Biological Systems.

 

Papers Submitted

 K. Simek and M. Kimmel. A computer algorithm of estimation of dynamics of multiple gene expression based on singular value decomposition. Submitted to  Mathematical Biosciences.

 

           

Published Abstracts (Recent)

1.                  R. Chakraborty, M. Kimmel, L. Jin, D.N. Stivers, Y. Zhong, D. Smelser, R. Deka. (1999) Repeat polymorphisms versus Simple Nucleotide Polymorphisms: Implications for genome diversity studies. Amer J Human Genet 65: A41.

2.                  M. Kimmel, R. Chakraborty, L. Jin, R. Deka (1999) Single Nucleotide Polymorphisms: Mathematical modeling of the ascertainment bias and a comparison with sample distributions. Amer J Human Genet 65: A84.

3.                  J.P. King, M. Kimmel, R. Chakraborty (1999) Microsatellite-based statistics for inferring the past population growth. Amer J Human Genet 65: A207.

4.                  V.S. Pankratz, M. Kimmel, R. Chakraborty (1999) Mutations and their effect on linkage disequilibrium mapping. Amer J Human Genet 65: A439.

5.                  R. Chakraborty, N. Wang, M. Kimmel, L. Jin, R. Deka, B. Budowle (2000) Evidence of frequent recurrent mutations at Single Nucleotide Polymorphism sites in the control region of the human mitochondrial genome. Amer J Human Genet 67: A88.

6.                  N. Wang, R. Chakraborty, M. Kimmel, L. Jin (2000)  Haplotype inference from genotype data of random samples from populations and detection of recombination between sites. Amer J Human Genet 67:  A89.

7.                  P.E. Bonnen, D. Trikka, Z. Fang, M.M. Weil, M. Kimmel, R. Chakraborty, D.L. Nelson (2000) Genome wide variation in LD:  Insights for association studies. . Amer J Human Genet 67:  A456.

8.                  A. Renwick, P. Bonnen, D. Trikka, D. Nelson, R. Chakraborty, M. Kimmel

9.                  (2000) Sampling properties of estimators of nucleotide diversity at discovered SNP sites. Amer J Human Genet 67:  A1192.

10.             M. Kimmel, R. Chakraborty (2000) Single Nucleotide Polymorphisms:  Effects of mutation, recombination and genetic drift. Amer J Human Genet 67:  A1278.

11.             S.R. Indugula, G. Sun, S. Chunhua, D. Smelser, R. Kaushal, H. Xu, M. Kimmel, Y. Zhong, R. Chakraborty, R. Deka (2000) Microsatellite loci in the HlA-Class 1 gene region show weak evidence of over-dominant selection. Amer J Human Genet 67:  A1280.

12.             H. Xu, A. Renwick, M. Kimmel, R. Deka, R. Chakrabort  (2000) Validity of homozygosity test of selective neutrallity at microsatellite loci. Amer J Human Genet 67:  A1289.

13.             R. Chakraborty, L. Jin, R. Deka, M. Kimmel (2001) .Extent and Pattern of Gene Diversity at Microsatellite Loci:  Implications for Disease-Gene Association Studies.  Amer J Human Genet 69:  A262.

14.             A. Renwick, P. Bonnen, D. Trikka, D. Nelson, R. Chakraborty, M. Kimmel (2001) Single-Nucleotide Polymorphisms at Several Cancer Susceptibility Genes Do Not Conform to the Infinite Site model of Mutation.  Amer J Human Genet 69:  A1380.

15.             H. Xu, A. Renwick, M. Kimmel, R. Chakraborty (2001) Effects of Population Substructure on the Homozygosity Test of Neutrality under the Stepwise Mutation Model. .  Amer J Human Genet69:  A1393.

16.             M. Kimmel, A. Renwick, R. Deka, R. Chakraborty (2001) Evolution of Microsatellite Loci and Past Demography of Modern Humans. .  Amer J Human Genet 69:  A1418.

 

 

Published Book Reviews

1.                  Pykh, Y.A. Equilibrium and Stability in Models of Population Dynamics. Nauka, Moscow 1983. Review 92009, Zentralblatt fur Mathematik, vol. 522, 1984.

2.                  Macken, C.A. and A.S. Perelson. Branching Processes Applied to Cell Surface Aggregation Phenomena. Lecture Notes in Biomathematics, vol. 58. Springer, Berlin 1985. Review 92001, Zentralblatt fur Mathematik, vol. 573, 1986.

3.                  Metz, J.A.J. and O. Diekmann (eds.) The Dynamics of Physiologically Structured Populations. Lecture Notes in Biomathematics, vol. 68. Springer, Berlin 1986. Review 92014, Zentralblatt fur Mathematik, vol. 614.

4.                  Wheldon, T.E. Mathematical Models in Cancer Research. Adam Hilger, Philadelphia 1988. Bull. Math. Biol. 51: 807-809, 1989.

5.                  Odell, G.M. and L.A. Segel. A Graphical Computer Package with Execises to Accompany Lee A. Segel's `Modeling Dynamic Phenomena in Molecular and Cellular Biology.' Version 2.02. Cambridge University Press, Cambridge 1987. The Quarterly Review of Biology 65: 539, 1990

6.                  Macken, C.A. and A.S. Perelson. Stem Cell Proliferation and Differentiation: A Multitype Branching Process Model. Springer-Verlag, Berlin 1988. Bull of Math Biol 53: 487-503, 1991.

7.                  Yakovlev, A.Y. and N.M. Yanev. Transient Process in Cell Proliferation Kinetics. Lecture Notes in Biomathematics. vol 82, Berilin, Springer-Verlag, 1989. Review 92008, Zentralblatt fur Mathematik, vol 714, 1991.

8.                  Yakovlev, A.Y. and A.V. Zorin. Computer Simulation in Cell Radiobiology. Springer-Verlag, Berlin. Zentralblatt fur Mathematik. (in press)

 

Textbook Example

Kimmel, M. Cell Dynamics. Application example in Ordinary Differential Equations with Modern Applications (Third Edition), by N. Finizio and G. Ladas. Wadsworth, Belmont, California, pp. 8-9, 1988.