Spring 2001 Mathematical Biology Seminar

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• 6 March at Rice
  3pm in DH 3076
  Keith Baggerly, Department of Biostatistics, MD Anderson Cancer Center
  
  Microarrays and Data Quality: Some Case Studies
  
  ABSTRACT: DNA microarrays are wonderful tools for measuring the relative expression levels of thousands of genes in a cell sample at once. Using microarrays, we can identify differential patterns of gene expression between tumor and normal cells, watch the cell cycle evolve through time, and possibly identify gene membership in regulatory pathways. Well, that's the theory. In this talk, I will present the results of some problems with real data that have been encountered as MD Anderson has set up its array facility. These will range from calibration (dilution experiments) to measurement (automatic artifact removal) to a basic analysis (some of the things that we report for a given array). I will finish by discussing some of our current active questions. The focus of the talk will be primarily on methods for analysis, so I won't be identifying specific genes this time.
  
  


• 20 April
  


• 18 May