Analysis of pairs of sequences (DNA)

2/18/03


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Table of Contents

Analysis of pairs of sequences (DNA)

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Dot-matrix plots

Dot-matrix plots

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Dynamic programming algorithms for finding optimal alignments

Needleman and Wunsch algorithm

Needleman and Wunsch algorithm

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Local alignment: Smith and Waterman algorithm

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Statistical significance of sequence similarities

Statistical significance of sequence similarities

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Score matrix for aminoacids

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Estimation of substitution probabilities

Estimation of substitution probabilities

Chapter 6 – work plan

Author: Marek Kimmel

Email: kimmel@rice.edu

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